Thymalin
Also known as: Timulina, Thymulin
Molecular Identifiers
Overview
Thymic bioregulatory peptide with a molecular weight of approximately 898 Da. Originally isolated from the thymus, it acts on T lymphocyte maturation and immune system regulation. Developed within the Russian peptide bioregulation school, it is used in short cycles to restore immune function and support thymus activity.
Thymic peptide complex — mixture of di/tripeptides extracted from the thymus, with no single defined sequence
Half-life
~3-5 hours
Administration Route
Subcutaneous or intramuscular
Category
Specialized Research
Mechanism of Action
- Promotion of T lymphocyte maturation and differentiation
- Regulation and restoration of immune system function
- Support for thymus function and regeneration
- Modulation of the balance between helper and suppressor T lymphocytes
- Stimulation of natural killer (NK) cell activity
Dosage Protocol
Data compiled from the literature. This does not constitute medical advice.
| Parameter | Value |
|---|---|
| Dose | 5-10 mg per injection |
| Frequency | Once daily |
| Timing | Morning |
| Duration | 5-10 days, cycled 2-4 times per year |
Reported Side Effects
Adverse effects described in the literature. Severity and frequency vary between individuals.
- Injection site pain
- Allergic reaction (rare)
- Mild transient fever
Presentations & Preparation
Vials of Thymalin found in the research market:
Reconstitution
- Diluent: Bacteriostatic water
- Volume: 2 ml per vial
- Slowly inject the diluent against the vial wall
- Gently swirl until fully dissolved
- Never shake
Storage
- Lyophilized: Refrigerated 2-8°C
- Reconstituted: Refrigerated 2-8°C (up to 30 days)
- Protect from direct light
- Do not freeze after reconstitution
Scientific Studies
Published studies on Thymalin.
Geroprotective effect of thymalin and epithalamin
Khavinson VKh, Morozov VG
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells
Khavinson VKh, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaia TV, Ivko OM
Peptide Drug Thymalin Regulates Immune Status in Severe COVID-19 Older Patients
Kuznik BI, Khavinson VKh, Shapovalov KG, Tsybikov NN, Lukyanov SA
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