Hexarelin
Also known as: Examorelin, HEX
Molecular Identifiers
Overview
First-generation synthetic hexapeptide GH secretagogue. Ghrelin receptor (GHS-R1a) agonist with greater potency than GHRP-6 but less selectivity than Ipamorelin. May elevate cortisol and prolactin.
His-D-2-Me-Trp-Ala-Trp-D-Phe-Lys-NH₂ Contains D-amino acids and modified amino acids
Half-life
~70 minutes
Administration Route
Subcutaneous
Category
GH Secretagogues
Mechanism of Action
- Potent GHS-R1a receptor agonism
- Robust stimulation of GH secretion
- Increase in serum IGF-1
- Cardioprotective effect independent of GH
- Possible desensitization with prolonged use
Dosage Protocol
Data compiled from the literature. This does not constitute medical advice.
| Parameter | Value |
|---|---|
| Dose | 200-300 mcg per injection |
| Frequency | 2-3 times per day |
| Timing | Morning, post-workout and evening |
| Duration | 8-12 weeks (with off periods) |
Reported Side Effects
Adverse effects described in the literature. Severity and frequency vary between individuals.
- Cortisol elevation
- Prolactin elevation
- Facial flushing
- Increased appetite
- Headache
- Water retention
Presentations & Preparation
Vials of Hexarelin found in the research market:
Reconstitution
- Diluent: Bacteriostatic water
- Volume: 1-2 ml per 2 mg vial
- Inject diluent slowly against the vial wall
- Gently swirl until dissolved
- Never shake
Storage
- Lyophilized: Room temperature or refrigerated
- Reconstituted: Refrigerated 2-8°C (up to 4 weeks)
- Protect from light
- Do not freeze after reconstitution
Related Peptides
CJC-1295 with DAC
1-2 mg per week · Once per week
CJC-1295 sem DAC
100-200 mcg per injection · 2-3 times daily
GHRP-2
100-300 mcg per injection · 2-3 times per day
GHRP-6
100-300 mcg per injection · 2-3 times per day
Ipamorelin
200-300 mcg per injection · 2-3 times daily
MK-677
10-25 mg per dose · Once daily