Cosmetic & Skin

Acetyl Octapeptide-1

Also known as: SNAP-25 fragment

Molecular Identifiers

Molecular Formula

C41H70N16O16S

PubChem CID

76283482

Molecular Weight

1075.17 Da

Overview

Acetylated octapeptide with anti-wrinkle properties that acts on neuromuscular junction modulation. Reduces facial expression lines by interfering with the release of neurotransmitters involved in muscle contraction.

Sequence (1 letter): EEMQRRAD

Extended notation: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂

Acetylated peptide — SNAP-25 fragment

Half-life

~2-3 hours

Administration Route

Topical or subcutaneous

Mechanism of Action

Modulation of the facial neuromuscular junction
Reduction of dynamic expression lines
Interference with acetylcholine release
Partial relaxation of facial musculature
Prevention of deepening of existing wrinkles

Dosage Protocol

Data compiled from the literature. This does not constitute medical advice.

Parameter	Value
Dose	Topical 3-5%
Frequency	Twice daily
Timing	Morning and evening
Duration	Continuous use

Reported Side Effects

Adverse effects described in the literature. Severity and frequency vary between individuals.

Local irritation
Redness
Skin sensitivity

Product Properties

Purity	>98%
Appearance	White lyophilized powder
Solubility	Soluble in water and bacteriostatic water
Source	Solid-phase peptide synthesis (SPPS)
Storage	Lyophilized: -20°C for up to 2 years, 2-8°C for up to 6 months. Reconstituted: 2-8°C for up to 4 weeks. Protect from light and moisture. Avoid repeated freeze-thaw cycles.