Decapeptide-12
Also known as: Lumixyl Peptide
Molecular Identifiers
Overview
10-amino acid peptide developed as a topical depigmenting agent. Competitively inhibits the tyrosinase enzyme, reducing melanin production without cytotoxicity to melanocytes.
Proprietary 10-amino acid sequence. Exact structure not published.
Half-life
Variable (topical use)
Administration Route
Topical
Category
Cosmetic & Skin
Mechanism of Action
- Competitive tyrosinase inhibition
- Reduction of melanin synthesis
- No cytotoxicity to melanocytes
- Gradual and uniform skin lightening
- Reversible mechanism (no permanent depigmentation)
Dosage Protocol
Data compiled from the literature. This does not constitute medical advice.
| Parameter | Value |
|---|---|
| Dose | Topical application |
| Frequency | 1-2 times daily |
| Timing | Morning and/or evening |
| Duration | 8-12 weeks for visible results |
Reported Side Effects
Adverse effects described in the literature. Severity and frequency vary between individuals.
- Mild skin irritation (rare)
Presentations & Preparation
Vials of Decapeptide-12 found in the research market:
Reconstitution
- Diluent: N/A (topical use)
- Volume: N/A
- Supplied as powder or topical formulations
- Typical concentration 100-200 ppm
Storage
- Lyophilized: Room temperature
- Reconstituted: N/A
- Protect from light and moisture
- Keep tightly sealed
Related Peptides
Acetyl Octapeptide-1
Topical 3-5% · Twice daily
AHK-Cu
Topical or 200-500 mcg subcutaneous · 1-2 times daily (topical), every other day (subcutaneous)
Argireline
Topical 5-10% or 100-250 mcg subcutaneous · Topical twice daily, subcutaneous 2-3x per week
GHK Basic
Topical or 200-600 mcg subcutaneous · 1-2 times daily (topical), every other day (subcutaneous)
Matrixyl
Topical application · 1-2 times daily
Melanotan I
0.5-1 mg per injection · Every other day (loading phase), weekly (maintenance)