Cosmetic & Skin

AHK-Cu

Also known as: Ala-His-Lys-Cu

Molecular Identifiers

Molecular Formula

C15H25CuN6O4

PubChem CID

169450582

Molecular Weight

416.9 Da

Overview

Copper tripeptide variant of GHK-Cu with alanine replacing glycine. Researched for its hair growth stimulation properties, collagen synthesis, and skin anti-aging effects.

Sequence (1 letter): AHK

Extended notation: Ala-His-Lys

Half-life

~2-4 hours

Administration Route

Topical or subcutaneous

Mechanism of Action

Stimulation of hair growth via follicle activation
Promotion of collagen and elastin synthesis
Anti-aging activity and dermal remodeling
Increased scalp vascularization
Modulation of hair-related growth factors

Dosage Protocol

Data compiled from the literature. This does not constitute medical advice.

Parameter	Value
Dose	Topical or 200-500 mcg subcutaneous
Frequency	1-2 times daily (topical), every other day (subcutaneous)
Timing	Preferably at night
Duration	8-12 weeks

Reported Side Effects

Adverse effects described in the literature. Severity and frequency vary between individuals.

Local irritation
Redness
Skin sensitivity

Product Properties

Purity	>98%
Appearance	Blue-violet lyophilized powder (photosensitive copper complex)
Solubility	Soluble in water and bacteriostatic water
Source	Solid-phase peptide synthesis (SPPS) with copper complexation
Storage	Lyophilized: -20°C for up to 2 years, 2-8°C for up to 6 months. Reconstituted: 2-8°C for up to 2 weeks. Protect from light (photosensitive). Avoid repeated freeze-thaw cycles.