BPC-157
Also known as: Body Protection Compound-157, Pentadecapeptídeo gástrico
Molecular Identifiers
Molecular Formula
C62H98N16O22
CAS Number
137525-51-0
PubChem CID
9941957Molecular Weight
1419.53 Da
Overview
Synthetic pentadecapeptide derived from a human gastric protective protein (BPC). Composed of 15 amino acids with the sequence GEPPPGKPADDAGLV, with a molecular weight of 1,419.53 Da. Stable in gastric juice and does not require a carrier for biological activity.
GEPPPGKPADDAGLV Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val Half-life
~4 hours
Administration Route
Subcutaneous or oral
Category
Healing & Recovery
Mechanism of Action
- VEGFR2 receptor upregulation and angiogenesis promotion
- Nitric oxide (NO) system modulation
- Interaction with the dopaminergic and GABAergic systems
- Promotion of GH receptor expression in tendons
- Cytoprotective effect on the gastrointestinal mucosa
Dosage Protocol
Data compiled from the literature. This does not constitute medical advice.
| Parameter | Value |
|---|---|
| Dose | 250-500 mcg per injection |
| Frequency | 1-2 times daily |
| Timing | Morning and/or evening |
| Duration | 4-8 weeks |
Reported Side Effects
Adverse effects described in the literature. Severity and frequency vary between individuals.
- Mild nausea (rare)
- Injection site pain
- Dizziness (rare)
Product Properties
| Purity | >99% |
| Appearance | White lyophilized powder |
| Solubility | Soluble in water |
| Source | Solid-phase peptide synthesis (SPPS) |
| Storage | Short-term: <4°C; Long-term: -20°C to -80°C |
Presentations & Preparation
Vials of BPC-157 found in the research market:
Reconstitution
- Diluent: Bacteriostatic water
- Volume: 1-2 ml per 5 mg vial
- Inject the diluent slowly against the vial wall
- Gently swirl — never shake
- Wait for complete dissolution (5-10 min if necessary)
Storage
- Lyophilized: Room temperature (up to 2 years)
- Reconstituted: Refrigerated 2-8°C (up to 4 weeks)
- Avoid freezing after reconstitution
- Protect from direct light
Scientific Studies
Published studies on BPC-157.
BPC 157 therapy to detriment sphincter dysfunction in rats
Sikiric P, Seiwerth S, Grabarevic Z, et al.
Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts
Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH
Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain demyelination and behavioral disturbances
Sikiric P, Seiwerth S, Rucman R, et al.
Related Peptides
ARA-290
2-4 mg per injection · Once daily
Cartalax
5-10 mg per day · Once daily
GHK-Cu
1-3 mg per injection · Once daily or every other day
LL-37
50-200 mcg per injection · Once daily
MGF
200-400 mcg per injection · Once daily (MGF) or 2-3 times per week (PEG-MGF)
TB-500
2-5 mg per injection · Twice per week