GHK-Cu
Also known as: Copper Peptide, Peptídeo de Cobre
Molecular Identifiers
Overview
Copper tripeptide (Gly-His-Lys-Cu²⁺) with collagen synthesis, wound healing, and anti-inflammatory properties. Naturally present in human plasma with levels that decline with age.
GHK Gly-His-Lys Half-life
~2-4 hours
Administration Route
Topical or subcutaneous
Category
Healing & Recovery
Mechanism of Action
- Promotion of type I and III collagen synthesis
- Stimulation of fibroblast proliferation
- Anti-inflammatory effect via cytokine modulation
- Attraction of immune cells for tissue repair
- Promotion of angiogenesis and nerve regeneration
Dosage Protocol
Data compiled from the literature. This does not constitute medical advice.
| Parameter | Value |
|---|---|
| Dose | 1-3 mg per injection |
| Frequency | Once daily or every other day |
| Timing | Preferably at night |
| Duration | 8-12 weeks |
Reported Side Effects
Adverse effects described in the literature. Severity and frequency vary between individuals.
- Mild skin irritation
- Local redness
- Transient pigmentation
Product Properties
| Purity | >98% |
| Appearance | Bluish lyophilized powder |
| Solubility | Soluble in water |
| Source | Chemical synthesis |
| Storage | Lyophilized: -20°C for up to 2 years, 2-8°C for up to 6 months. Reconstituted: 2-8°C for up to 2 weeks. Protect from light (photosensitive copper complex). Avoid repeated freeze-thaw cycles. |
Presentations & Preparation
Vials of GHK-Cu found in the research market:
Reconstitution
- Diluent: Bacteriostatic water
- Volume: 2 ml per vial
- Slowly inject the diluent along the vial wall
- Gently swirl until fully dissolved
- Solution should have a slight bluish tint
Storage
- Lyophilized: Refrigerated 2-8°C
- Reconstituted: Refrigerated 2-8°C (up to 30 days)
- Protect from direct light
- Do not freeze after reconstitution
Scientific Studies
Published studies on GHK-Cu.
Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data
Pickart L, Vasquez-Soltero JM, Margolina A
The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging
Pickart L, Margolina A
Related Peptides
ARA-290
2-4 mg per injection · Once daily
BPC-157
250-500 mcg per injection · 1-2 times daily
Cartalax
5-10 mg per day · Once daily
LL-37
50-200 mcg per injection · Once daily
MGF
200-400 mcg per injection · Once daily (MGF) or 2-3 times per week (PEG-MGF)
TB-500
2-5 mg per injection · Twice per week