Epithalon
Also known as: Epitalon, Epithalone
Molecular Identifiers
Overview
Tetrapeptide (Ala-Glu-Asp-Gly) telomerase activator. Anti-aging research. Short repeated cycles throughout the year. Supports pineal gland function and circadian rhythm.
AEDG Ala-Glu-Asp-Gly Half-life
~2-3 hours
Administration Route
Subcutaneous or intramuscular
Category
Cognitive & Neuroprotective
Mechanism of Action
- Telomerase activation and telomere maintenance
- Pineal gland function support
- Circadian rhythm regulation
- Antioxidant properties
- Modulation of aging-related gene expression
Dosage Protocol
Data compiled from the literature. This does not constitute medical advice.
| Parameter | Value |
|---|---|
| Dose | 5-10 mg per injection |
| Frequency | Once daily or every other day |
| Timing | Preferably in the evening |
| Duration | 10-20 days, cycled 2-4 times per year |
Reported Side Effects
Adverse effects described in the literature. Severity and frequency vary between individuals.
- Injection site pain (rare)
- Mild headache (rare)
Presentations & Preparation
Vials of Epithalon found in the research market:
Reconstitution
- Diluent: Bacteriostatic water
- Volume: 2 ml per vial
- Slowly inject the diluent against the vial wall
- Gently swirl until fully dissolved
- Never shake
Storage
- Lyophilized: -20°C or refrigerated 2-8°C
- Reconstituted: Refrigerated 2-8°C (up to 30 days)
- Protect from direct light
- Do not freeze after reconstitution
Scientific Studies
Published studies on Epithalon.
Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice
Anisimov VN, Khavinson VKh, Popovich IG, Zabezhinski MA
Peptide regulation of aging: the tissue-specific effect of epithalon on the chromosome telomere length
Khavinson VKh, Bondarev IE, Butyugov AA
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