FG Loop
Also known as: FGL, NCAM peptide
Overview
Peptide derived from neural cell adhesion molecule (NCAM). Activates FGFR receptors, promoting synaptic plasticity and neuroprotection. Researched for cognitive enhancement, neural recovery, and neurodegenerative diseases.
Research peptide — sequence derived from the FG loop of neural cell adhesion molecule (NCAM)
Half-life
~1-3 hours
Administration Route
Subcutaneous
Category
Cognitive & Neuroprotective
Mechanism of Action
- Activation of FGFR receptors (fibroblast growth factor receptor)
- Promotion of synaptic plasticity and long-term potentiation (LTP)
- Neuroprotection against excitotoxicity and oxidative stress
- Mimicry of NCAM function in neural signaling
- Support for neuronal survival and differentiation
Dosage Protocol
Data compiled from the literature. This does not constitute medical advice.
| Parameter | Value |
|---|---|
| Dose | 5-10 mg per subcutaneous injection |
| Frequency | Once daily or every other day |
| Timing | Morning or per protocol |
| Duration | 2-4 weeks |
Reported Side Effects
Adverse effects described in the literature. Severity and frequency vary between individuals.
- Injection site pain
- Mild headache
Presentations & Preparation
Vials of FG Loop found in the research market:
Reconstitution
- Diluent: Bacteriostatic water
- Volume: 2 ml per vial
- Inject the diluent slowly against the vial wall
- Gently swirl until fully dissolved
- Never shake
Storage
- Lyophilized: Refrigerated 2-8°C
- Reconstituted: Refrigerated 2-8°C (up to 30 days)
- Protect from direct light
- Do not freeze after reconstitution
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